Skin Detachment and Regrowth in Toxic Epidermal Necrolysis
نویسندگان
چکیده
Toxic epidermal necrolysis is a rare but clinically well-described dermatological pathology. However, clinical pictures of this disorder in text books do not reflect its dynamic evolution. Usually, the desquamative post-bullous stage is represented, neglecting the initial bullous stage as well as the skin healing. With one clinical case, we provide a day-after-day illustration of the evolution of a patient suffering from toxic epidermal necrolysis. During one month, a skin area of a limb was regularly photo-documented.
منابع مشابه
Toxic Epidermal Necrolysis and Stevens-Johnson Syndrome
The term toxic epidermal necrolysis (TEN) was introduced in 1956 by Lyell to describe four patients with a syndrome featured by extensive epidermal detachment with mucous membrane involvement, leaving the skin surface looking scalded. Necrolysis denotes necrosis and full thickness detachment of the epidermis. Toxic means severe constitutional symptoms and complications. Stevens-Johnson syndrome...
متن کاملAntibiotic-induced Toxic Epidermal Necrolysis - A Case Report.
Toxic epidermal necrolysis (TEN) is severe cutaneous hypersensitivity reaction characterized by necrosis of the epidermis and detachment of the epidermis and dermis that usually occurs as an idiosyncratic reaction to certain drugs. We report the case of a patient admitted to our Intensive Care Unit after an above-the-knee amputation who developed toxic epidermal necrolysis, possibly resulting f...
متن کاملTreatment of Severe Drug Reactions 1. Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
SJS and TEN are variants of the same process, presenting as severe mucosal erosions with widespread erythematous, cutaneous macules or atypical targets. The cutaneous lesions often become confluent and show a positive Nikolsky sign and epidermal detachment. In SJS, epidermal detachment involves less than 10% of the total body skin area; transitional SJS-TEN is defined by an epidermal detachment...
متن کاملTreatment of Severe Drug Reactions 1. Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
SJS and TEN are variants of the same process, presenting as severe mucosal erosions with widespread erythematous, cutaneous macules or atypical targets. The cutaneous lesions often become confluent and show a positive Nikolsky sign and epidermal detachment. In SJS, epidermal detachment involves less than 10% of the total body skin area; transitional SJS-TEN is defined by an epidermal detachment...
متن کاملCarbamzepine-induced toxic epidermal necrolysis
Toxic epidermal necrolysis (TEN), also known as Lyell's syndrome, is a widespread life-threatening mucocutaneous disease where there is extensive detachment of the skin and mucous membrane. Many factors involved in the etiology of TEN including adverse drug reactions. Here we are reporting a case of toxic epidermal necrolysis in an adult male patient after receiving carbamazepine in a 38 year o...
متن کامل